Cataplex® E for Dogs by Standard Process: Benefits, Uses, Safety
As a holistic veterinarian, I am often asked about supplements that can support whole body health in dogs, especially when pet parents want something food-based and thoughtfully formulated. One supplement that comes up often is Cataplex® E by Standard Process.
Although Cataplex E was originally developed for humans, it is commonly used in veterinary practice to support dogs who may benefit from extra antioxidant, reproductive, vascular, or thyroid support. When used appropriately, it can be a valuable addition to a dog’s wellness plan.
Let’s walk through what Cataplex E is, how it works, and when I consider it helpful for dogs.

What Is Cataplex® E by Standard Process?
Cataplex E is a whole food-based vitamin E supplement that also provides selenium and a proprietary blend of organ and plant ingredients. It is designed to support cellular health, antioxidant balance, and healthy thyroid function.
This supplement focuses on nourishment at the cellular level, meaning it supports how cells communicate, repair, and protect themselves from oxidative stress.
A Quick Note on Standard Process
Standard Process has been producing whole food supplements since 1929. Their approach centers on food-based nutrients, controlled manufacturing, and consistent quality testing. Cataplex E has been part of their lineup for decades and is widely used in both human and veterinary wellness settings.
Key Benefits of Cataplex® E for Dogs
Cataplex E supports multiple body systems at once. That versatility is one of the reasons I reach for it in practice.
Antioxidant Support
Vitamin E and selenium are both antioxidants. Antioxidants help neutralize free radicals, which are unstable molecules that can damage cells over time. Supporting antioxidant balance is especially helpful for aging dogs, active dogs, or dogs under physical stress.
Thyroid and Metabolic Support
Selenium is required for the production and regulation of thyroid hormones. These hormones influence metabolism, energy levels, and overall cellular function. Adequate selenium supports healthy thyroid activity and normal metabolic processes.
Reproductive Health Support
Cataplex E contains bovine orchic extract, which has traditionally been used to support reproductive tissue health. This is most often considered for intact dogs during breeding years, but it can also support overall endocrine balance.
Vascular and Circulatory Health
Vitamin E supports healthy blood vessels and circulation by protecting the delicate lining of blood vessels from oxidative damage. This can be helpful for dogs where cardiovascular support is part of the wellness picture.
Immune System Support
Several ingredients in the proprietary blend, including spleen extracts and whole food nutrients, support immune system function. These ingredients provide building blocks that help the immune system respond appropriately.

How Cataplex® E Works in the Body
Cataplex E works by supplying nutrients that the body already uses every day.
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Vitamin E protects cell membranes and supports immune signaling.
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Selenium supports thyroid hormone metabolism and DNA synthesis.
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Whole food organ extracts provide naturally occurring cofactors that support cellular communication.
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Antioxidant support helps reduce oxidative stress, which can affect many body systems at once.
Rather than targeting a single symptom, Cataplex E supports underlying biological processes.
Ingredients in Cataplex® E by Standard Process
Each serving size of two tablets provides:
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Vitamin E: 3.3 mg
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Selenium: 11 mcg
Proprietary Blend (510 mg)
This blend includes:
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Bovine orchic extract
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Inositol
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Organic pea vine juice powder
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Ribonucleic acid (RNA)
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Bovine adrenal
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Organic beet root
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Organic oat flour
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Bovine spleen
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Ovine spleen
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Bovine liver
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Manganese lactate
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Ascorbic acid
Other Ingredients
Honey, selenium yeast, d-alpha tocopherol (vitamin E from sunflower), modified tapioca starch, acacia gum, and calcium stearate.
Each ingredient serves a purpose, whether supporting metabolism, immune health, antioxidant balance, or cellular repair.

When I Consider Cataplex® E for Dogs
Cataplex E may be appropriate for dogs who need support in areas such as:
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Antioxidant and cellular health
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Thyroid and metabolic balance
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Reproductive system support
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Immune system resilience
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Skin and coat health related to oxidative stress
As with any supplement, context matters. I always look at the whole dog, including diet, age, health history, and current medications.
Dosage and Administration for Dogs
Standard Process suggests:
Two tablets per meal, or as directed.
In veterinary use, I typically adjust dosing based on size:
| Dog Size | Suggested Amount |
|---|---|
| Small dogs (1 to 20 lb) | 1 tablet daily |
| Medium dogs (21 to 50 lb) | 2 tablets daily |
| Large dogs (51 lb and up) | 3 tablets daily |
Tablets can be given whole or crushed and mixed into food.

Possible Side Effects and Safety Notes
Cataplex E is generally well tolerated. In some dogs, mild digestive upset such as loose stool or vomiting may occur, especially if introduced too quickly.
If this happens, I recommend lowering the dose and slowly increasing again. Always consult your veterinarian if your dog has underlying conditions or is on medication.
Frequently Asked Questions
What is Cataplex® E used for in dogs?
Cataplex E is used to support antioxidant balance, thyroid function, reproductive health, immune support, and cellular health in dogs.
Is Cataplex® E safe for long term use?
When used appropriately and under veterinary guidance, it is commonly used long term as part of a wellness plan.
Does Cataplex® E support thyroid health?
Yes. Selenium plays a key role in thyroid hormone metabolism and helps support normal thyroid function.
Can puppies take Cataplex® E?
Supplement use in puppies should always be discussed with a veterinarian to ensure proper dosing and timing.
Should I give Cataplex® E with food?
Yes. Giving it with meals helps improve tolerance and absorption.
