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Neurotrophin PMG® for Dogs by Standard Process: Brain and Nerve Health, Care and Use

The following information is a summary and review based on Dr. Candy's professional experience and recommendations. Any summary or statement has not been provided nor influenced by the manufacturer.


If you are caring for a dog with nerve concerns, cognitive changes, or neurological stress, you know how unsettling that can feel. In my practice, one of the supplements I reach for when the nervous system needs extra support is Neurotrophin PMG® by Standard Process.

This formula is designed to support brain tissue and nerve function using targeted whole food extracts. It is not a medication, but it can be a valuable part of a thoughtful, holistic support plan.

Let’s walk through what it is, how it works, and when I consider using it.

Standard Process Neurotrophin PMG for Dogs Journeys Holistic Life

What Is Neurotrophin PMG®?

Neurotrophin PMG® is a nervous system support supplement made with porcine brain PMG™ extract. PMG stands for Protomorphogen™, which refers to specific protein based compounds derived from healthy animal tissue.

In simple terms, Protomorphogens provide structural and nutritional signals that support specific organs and tissues. In this case, the focus is the brain and nervous system.

Standard Process has used this approach since the early 1900s, relying on whole food extracts rather than isolated synthetic nutrients.

Why the Brain and Nervous System Need Support

The brain is the control center of the body. Nerves act like electrical wiring, sending messages that control movement, sensation, behavior, and organ function.

When nerve tissue is stressed, aging, inflamed, or not functioning efficiently, dogs may show signs such as:

  • Changes in coordination or balance

  • Tremors or nerve sensitivity

  • Cognitive decline or confusion

  • Increased anxiety or nervous behavior

  • Slower response times

Supporting nerve tissue early and consistently can help maintain quality of life, especially in senior dogs or those with chronic neurological challenges.

How Neurotrophin PMG® Works

Neurotrophin PMG® supports the nervous system in three main ways.

Targeted Tissue Support

The porcine brain PMG™ extract provides peptides and nucleotides that are specific to brain tissue. These compounds help support normal cellular communication and tissue integrity.

Mineral Support for Nerve Signaling

Magnesium plays an important role in nerve transmission and muscle relaxation. Including magnesium citrate helps support proper nerve signaling and metabolic balance.

Cellular and Immune Balance

By supporting healthy cells and tissue recognition, PMG supplements are often used to help the immune system respond appropriately to stressed or damaged tissue.

This is not a stimulant and not a sedative. It is nutritional support for tissue function.


5900-20-Neurotrophin-PMG for dogs

Key Benefits I Look For in Dogs

When used appropriately, Neurotrophin PMG® may help support:

  • Brain tissue health and function

  • Healthy nerve signaling

  • Cognitive clarity in aging dogs

  • Neurological resilience during stress or recovery

  • Overall nervous system balance

Every dog responds differently, and this supplement works best as part of a broader plan that includes diet, lifestyle, and other supportive therapies.

Ingredient Breakdown and What They Do

Each tablet contains carefully selected ingredients that work together.

Active Nutrients Per Tablet

  • Cholesterol 10 mg
    Cholesterol is a critical component of cell membranes and is especially important in brain tissue.

  • Sodium 15 mg
    Sodium supports nerve impulses and fluid balance in the body.

Proprietary Blend 200 mg

  • Porcine brain PMG™ extract
    Provides tissue specific peptides and nucleotides that support brain and nerve cells.

  • Magnesium citrate
    Supports nerve transmission, muscle relaxation, and metabolic processes.

Other Ingredients

  • Calcium lactate

  • Cellulose

  • Calcium stearate

These ingredients help with tablet structure and stability.

Standard Process Neurotrophin PMG for Dogs

When I Consider Using Neurotrophin PMG®

This supplement is often used in dogs needing additional nervous system support, including those with:

  • Age related cognitive changes

  • Neurological stress or weakness

  • Tremors or nerve sensitivity

  • Behavioral changes linked to nervous system imbalance

It is not intended to replace medical treatment. I use it as a supportive tool alongside appropriate veterinary care.

Dosage and Administration for Dogs

Neurotrophin PMG® tablets are best given on an empty stomach for optimal absorption.

General Dosing Guidelines

Dog Size Suggested Amount
1 to 20 lbs 2 tablets daily
21 to 50 lbs 3 tablets daily
51 lbs and up 4 tablets daily


These are general guidelines. Individual needs can vary based on health status and goals.

How to Give It

Most dogs will take the tablets willingly. If needed, you can hide them in a small amount of food like cheese or meat. Make sure the full dose is consumed.

Always provide fresh water.

Neurotrophin PMG for Dogs by Standard Process

Safety and Possible Side Effects

Neurotrophin PMG® is generally well tolerated when used as directed.

Possible Reactions

Some dogs may experience mild digestive upset when starting any new supplement. Rarely, dogs with ingredient sensitivities may show itching or skin changes.

If you notice anything concerning, stop the supplement and check in with your veterinarian.

Important Precautions

  • Do not exceed recommended dosing

  • Use caution in dogs with known ingredient sensitivities

  • If your dog is pregnant or nursing, consult your veterinarian first

Final Thoughts

Supporting the nervous system can make a meaningful difference in how a dog feels, moves, and interacts with the world. Neurotrophin PMG® offers targeted nutritional support for brain and nerve tissue using a whole food based approach.

It is one of the tools I use when the nervous system needs extra care, especially in aging dogs or those under neurological stress.

If you are unsure whether this supplement is appropriate for your dog, I always recommend discussing it with your veterinarian or working with a holistic practitioner who can look at the full picture.


Frequently Asked Questions

What is Neurotrophin PMG® used for in dogs?
Neurotrophin PMG® is used to support brain tissue and nervous system function. It is often included in wellness plans for dogs with cognitive changes, neurological stress, or age related nerve support needs.

How does Neurotrophin PMG® support the nervous system?
It provides tissue specific peptides and nucleotides from porcine brain along with magnesium to support nerve signaling, cellular communication, and tissue health.

Is Neurotrophin PMG® a medication?
No. It is a nutritional supplement designed to support normal function. It does not treat or cure disease and should not replace medical care.

How long does it take to see results?
Response time varies. Some dogs show changes within a few weeks, while others benefit gradually over time with consistent use.

Where can I purchase Neurotrophin PMG® for dogs?
Neurotrophin PMG® is available directly through me at Journeys Holistic Life.