Hepatrophin PMG for Dogs by Standard Process: Liver Causes and Care
When pet parents ask me about liver support, I always start with one simple truth. The liver does a lot of heavy lifting. It filters toxins, stores nutrients, supports digestion, and helps regulate metabolism. When the liver is stressed, the whole body feels it.
Hepatrophin PMG by Standard Process is one of the supplements I often discuss when a dog needs gentle, targeted liver support. It has a long history of use and a very specific role. In this article, I will walk you through what it is, how it works, when it may help, and how to use it safely.

What Is Hepatrophin PMG by Standard Process?
Hepatrophin PMG is a liver support supplement made by Standard Process. It is designed to support healthy liver tissue and normal liver function.
This product is not a drug and it does not force the liver to detox faster. Instead, it provides nutritional support that helps the liver do its job more efficiently.
Understanding Hepatrophin PMG
Hepatrophin PMG contains bovine liver PMG extract. PMG stands for protomorphogen.
A protomorphogen is a specific cellular blueprint from a healthy organ. In simple terms, it provides targeted nutritional signals that support the structure and function of that same organ in the body.
In this case, bovine liver PMG extract supports liver cells and liver tissue.
Background and Clinical Use
Standard Process has produced whole food based supplements for over 90 years. Hepatrophin PMG was developed using their proprietary extraction process, which preserves important nucleotides and peptides found in liver tissue.
Veterinarians have used this product for decades as part of a broader liver support plan. It is commonly paired with diet changes, lifestyle adjustments, and other supplements when needed.
How Hepatrophin PMG Supports Whole Body Health
When the liver works well, many other systems benefit.
Dogs with liver stress may show vague signs such as low energy, poor appetite, digestive upset, or changes in stool. Supporting liver function can help stabilize these systems over time.
This product is not meant to replace medical treatment. It works best as nutritional support alongside appropriate veterinary care.

Key Benefits of Hepatrophin PMG for Dogs
Liver support is not just about detox. It is about helping the liver stay resilient and functional over time.
Hepatrophin PMG may help by:
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Supporting normal liver cell structure
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Assisting the liver’s natural detoxification pathways
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Supporting nutrient storage and metabolism
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Promoting overall metabolic balance
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Supporting immune related liver stress
Because the liver plays a role in digestion, hormone processing, and immune function, supporting liver health often has wide ranging benefits.
Ingredients in Hepatrophin PMG by Standard Process
Keeping ingredients simple and purposeful matters. Hepatrophin PMG contains only a few components.
Active Ingredients per Tablet
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Sodium: 30 mg
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Bovine liver PMG extract: 320 mg
Other Ingredients
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Honey
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Calcium stearate
Why These Ingredients Matter
Bovine liver PMG extract provides a unique profile of nucleotides and peptides derived from healthy liver tissue. These compounds help support liver cell integrity and normal metabolic function.
Sodium plays a role in normal cellular activity and fluid balance. The amount included is modest and appropriate for most dogs.
Honey improves palatability and helps the tablet dissolve easily. Calcium stearate is used to maintain tablet consistency.

When Hepatrophin PMG May Be Helpful
I often discuss this supplement in dogs with increased liver workload or chronic metabolic stress.
This may include dogs with:
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Chronic liver enzyme elevation
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Age related liver stress
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Metabolic disorders that burden the liver
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Immune mediated conditions affecting liver tissue
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Environmental or dietary toxin exposure
Each dog is different. Liver support should always be tailored to the individual.
How Hepatrophin PMG Works in the Body
Hepatrophin PMG supports the liver in three main ways.
First, it supports detoxification by nourishing liver cells that process waste and toxins.
Second, it supports cellular repair and maintenance, helping liver tissue stay resilient.
Third, it supports immune balance within the liver, which can be important in inflammatory conditions.
Dosage and Administration for Dogs
Proper dosing matters. Always work with your veterinarian when adding a new supplement.
General Dosing Guidelines
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Small dogs up to 20 pounds: 2 tablets daily
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Medium dogs 21 to 50 pounds: 3 tablets daily
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Large dogs over 50 pounds: 4 tablets daily
I often individualize dosing based on the dog’s condition, diet, and overall plan.
How to Give Hepatrophin PMG
This supplement is best given on an empty stomach.
The tablet can be offered by hand or hidden in a small amount of food. Most dogs tolerate the taste well due to the honey content.
Consistency matters more than speed. Slow, steady support is often best for the liver.

Possible Side Effects and Safety Considerations
Most dogs tolerate Hepatrophin PMG very well.
Occasionally, mild digestive upset such as loose stool or vomiting may occur. Allergic reactions are rare but possible.
If you notice vomiting, diarrhea, itching, swelling, or breathing changes, stop the supplement and contact your veterinarian.
Always introduce new supplements gradually and avoid exceeding recommended doses.
Important Precautions
If your dog has diagnosed liver disease, is on prescription medication, or has complex health conditions, consult your veterinarian before starting this supplement.
Hepatrophin PMG is nutritional support, not a replacement for diagnostics or medical treatment.
Final Thoughts on Hepatrophin PMG for Dogs
Liver health often gets overlooked until there is a problem. Supporting the liver early and consistently can make a meaningful difference over time.
Hepatrophin PMG by Standard Process offers targeted, whole food based liver support when used thoughtfully and appropriately. When paired with proper diet, lifestyle care, and veterinary oversight, it can be a valuable part of a liver support plan.
If you are unsure whether this supplement is right for your dog, I recommend discussing it with a veterinarian who understands holistic nutrition and liver health.
Frequently Asked Questions
What is Hepatrophin PMG by Standard Process used for in dogs?
Hepatrophin PMG is used to support healthy liver tissue, normal detoxification, and metabolic function in dogs.
How does Hepatrophin PMG support the liver?
It provides bovine liver protomorphogen extract, which supplies targeted nutritional support for liver cells and liver structure.
How long does it take to see results?
Response time varies. Some dogs show improvements in energy or digestion within a few weeks, while others require longer support.
Is Hepatrophin PMG safe for long term use?
When used as directed and under veterinary guidance, it is commonly used for extended periods.
Can cats take Hepatrophin PMG?
Although originally formulated for humans, veterinarians have used Hepatrophin PMG in both dogs and cats for many years. Dosing should always be adjusted and guided by a veterinarian.
