Pituitrophin PMG® for Dogs by Standard Process: Hormone Balance, Care & Support

As a holistic veterinarian, I look at the whole dog. Hormones, stress, growth, metabolism. They are all connected.

One supplement I use when I want to support the endocrine system is Standard Process Pituitrophin PMG®. It is designed to support the pituitary gland, often called the master gland.

If your dog is dealing with hormone imbalance, suspected pituitary stress, or conditions like Cushing’s disease, this is a product you may hear about in my practice.

What Is Pituitrophin PMG®

Pituitrophin PMG is a glandular supplement that supports the pituitary gland.

The pituitary is a small gland at the base of the brain. It controls:

• Growth

• Metabolism

• Reproduction

• Stress response

• Thyroid and adrenal signaling

When this gland is under stress, many systems in the body can be affected.

Pituitrophin PMG contains a proprietary bovine pituitary Protomorphogen extract. A Protomorphogen is a cellular extract developed using technology created by Dr. Royal Lee. It provides tissue specific nucleotides and peptides that help support normal cellular function.

From the manufacturer:

• Contains bovine pituitary PMG™ extract

• Provides a unique profile of nucleotides and peptides

• Uses Standard Process proprietary extraction technology

• Available only through Standard Process

Each tablet contains:

• Calcium 30 mg

• Proprietary blend 115 mg:

  • Magnesium citrate

  • Bovine pituitary PMG™ extract

• Other ingredients:

  • Calcium lactate

  • Cellulose

  • Calcium stearate

No artificial flavors. No unnecessary fillers.

Why the Pituitary Gland Matters in Dogs

I explain it to clients this way.

If the endocrine system is an orchestra, the pituitary is the conductor.

It signals the:

• Thyroid gland

• Adrenal glands

• Reproductive organs

• Growth hormone pathways

When the signaling is off, we may see:

• Excess thirst and urination

• Hair thinning

• Weight gain

• Muscle loss

• Low energy

• Behavior changes

One common condition linked to pituitary dysfunction is Cushing’s disease, also called hyperadrenocorticism. Many cases are caused by a pituitary tumor that overstimulates the adrenal glands.

Pituitrophin PMG is not a cure for Cushing’s. But it can be used as part of a broader integrative plan to support glandular balance.

Benefits of Pituitrophin PMG for Dogs

Here is how I use it clinically.

Supports Balanced Endocrine Function

The bovine pituitary extract provides tissue specific support. The goal is to help the body maintain normal signaling between glands.

Helps Manage Pituitary Related Stress

In dogs with suspected pituitary strain, I may include this in a comprehensive protocol that also addresses diet, liver support, and adrenal balance.

Supports Normal Repair Processes

Protomorphogen extracts are designed to support healthy cellular function. This may help the body maintain normal tissue repair mechanisms.

Provides Foundational Mineral Support

Magnesium citrate supports:

• Nerve function

• Muscle function

• Cellular metabolism

Calcium supports:

• Bone health

• Muscle contraction

• Hormone signaling

This combination gives both glandular and mineral support.

When I Consider Pituitrophin PMG

I may evaluate this supplement in dogs with:

• Suspected pituitary driven Cushing’s

• Hormone imbalances

• Growth abnormalities

• Chronic stress patterns

• Endocrine instability

Every case is different. I always recommend lab work and proper diagnostics first. Supplements should support a plan, not replace testing.

Dosage and How to Give It

General manufacturer guidelines:

Best given on an empty stomach when possible.

Administration tips:

• Give directly as a treat

• Hide in a small amount of food if needed

• Be consistent with timing

Always confirm dosing with your veterinarian, especially if your dog is on medications.

Possible Side Effects

Most dogs tolerate Pituitrophin PMG well.

Occasionally I may see mild digestive upset, such as:

• Loose stool

• Vomiting

• Decreased appetite

If you notice changes, stop the supplement and consult your veterinarian.

Use caution in dogs with complex endocrine disease. These cases require monitoring.

Safety and Professional Guidance

Before starting Pituitrophin PMG:

• Get appropriate bloodwork

• Confirm diagnosis

• Review current medications

• Work with a veterinarian familiar with endocrine disease

This supplement is not a substitute for conventional treatment when it is required. It is part of an integrative strategy.

If you are building a complete endocrine support plan, you may also want to explore adrenal and liver support options inside my educational resource library on Journeys Holistic Life.

My Clinical Perspective

I like Pituitrophin PMG because it is targeted, doesn't overstimulate the system, and provides tissue specific support. In the right patient, it can be a helpful piece of a well designed protocol.

Hormone balance is rarely about one gland. It is about the whole system. Diet, stress, sleep, inflammation, liver health. They all matter.

When we support the body intelligently, we often see better long term stability.

Frequently Asked Questions

What does Pituitrophin PMG do for dogs?

It supports the health and normal function of the pituitary gland, which helps regulate growth, metabolism, stress response, and other endocrine glands.

Can Pituitrophin PMG treat Cushing’s disease?

No supplement treats Cushing’s disease. It may be used as part of an integrative plan to support glandular balance, but proper diagnosis and medical guidance are essential.

Is Pituitrophin PMG safe for long term use?

In many cases it is well tolerated, but long term use should be supervised by a veterinarian, especially in dogs with endocrine disorders.

Can I use this with other medications?

Possibly, but always discuss this with your veterinarian first. Hormonal conditions require careful monitoring.

How quickly will I see results?

That depends on the dog and the condition. Some dogs show gradual improvement over weeks. Endocrine support is typically a long term strategy, not a quick fix.