B6-Niacinamide for Dogs: Energy, Nerve & Skin Support
As pet parents, we put a lot of thought into food, exercise, and daily routines. What often gets overlooked is how important B vitamins are for dogs, especially when a dog is under stress, aging, or dealing with chronic health concerns.
One supplement I reach for often is B6-Niacinamide for Dogs by Standard Process. It is a simple formula, but it plays a big role in supporting energy, the nervous system, digestion, and skin health.
Let me walk you through what it is, how it works, and when it can be helpful for dogs.

What Is B6-Niacinamide by Standard Process?
B6-Niacinamide is a whole-food-based supplement made by Standard Process. It combines two essential B vitamins:
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Vitamin B6, also called pyridoxine
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Niacinamide, a gentle form of vitamin B3
These vitamins are involved in hundreds of metabolic processes in the body. In simple terms, they help the body turn food into energy, support nerve signaling, and keep skin and tissues healthy.
Unlike synthetic-only formulas, this supplement includes food-based ingredients that help the body recognize and use these vitamins more effectively.
Why B6 and Niacinamide Matter for Dogs
B vitamins are water soluble. Dogs do not store large amounts of them. Stress, illness, medications, poor digestion, and aging can all increase a dog’s need for B vitamins.
Here is what these two do specifically:
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Vitamin B6 supports protein metabolism, red blood cell formation, and neurotransmitters. Neurotransmitters are chemical messengers that help nerves communicate.
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Niacinamide supports energy production, circulation, skin health, and normal nervous system function.
When dogs are low in B vitamins, I often see low energy, poor coat quality, digestive issues, and increased anxiety or irritability.

Health Benefits of B6-Niacinamide for Dogs
Supports the Nervous System and Stress Response
B6 is required to make neurotransmitters that help regulate mood and behavior. Dogs dealing with anxiety, restlessness, or cognitive changes often benefit from additional B vitamin support.
Helps Maintain Healthy Skin and Coat
Niacin plays a role in skin barrier function and circulation. Dogs with dry skin, dull coats, or chronic itching may benefit from this type of support alongside diet changes.
Supports Energy and Metabolism
B6 and niacinamide help convert proteins, fats, and carbohydrates into usable energy. This can be helpful for dogs with low stamina, recovery needs, or chronic illness.
Digestive and Gut Support
Vitamin B6 supports normal digestive enzyme function. When digestion improves, dogs absorb nutrients more efficiently, which supports overall health.
Cardiovascular and Circulatory Support
Niacin supports circulation and red blood cell health, which helps deliver oxygen throughout the body.
Ingredient Breakdown and What Each One Does
Each tablet contains carefully selected ingredients that work together.
Niacin (10 mg)
Supports energy metabolism, circulation, skin health, and nerve function.
Vitamin B6 (50 mg)
Supports brain and nerve function, red blood cell production, and protein metabolism.
Proprietary Whole Food Blend (250 mg)
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Nutritional yeast: A natural source of B vitamins and amino acids
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Bovine liver: Rich in bioavailable vitamins and minerals
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Organic reishi mushroom powder: Supports immune balance
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Organic shiitake mushroom powder: Provides antioxidants and immune support
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Ascorbic acid: Vitamin C for antioxidant and tissue support
Other Ingredients
Pyridoxine hydrochloride, honey, niacinamide, calcium stearate, and arabic gum help stabilize and deliver the nutrients effectively.

When I Commonly Use B6-Niacinamide in Dogs
This supplement is often helpful for dogs with:
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Anxiety, nervousness, or stress sensitivity
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Chronic skin or coat concerns
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Digestive inefficiency or poor appetite
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Low energy or slow recovery
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Support needs for the nervous or cardiovascular systems
It is not a stimulant. It supports normal physiology so the body can function more efficiently.
Dosage and How to Give It
Typical Dosage Guidelines
| Dog Size | Amount |
|---|---|
| Small dogs 1 to 20 lbs | 1 tablet daily |
| Medium dogs 21 to 50 lbs | 2 tablets daily |
| Large dogs over 50 lbs | 3 tablets daily |
The manufacturer lists one tablet per day as a general guideline. In clinical practice, dosing is often adjusted based on size and individual needs.
Always start low and increase gradually unless directed otherwise.
Administration Tips
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Tablets can be given whole or crushed
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Mix with food for picky eaters
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Crushing and blending with a small amount of wet food usually works well

Possible Side Effects and Safety
B6-Niacinamide is generally very well tolerated. Side effects are uncommon.
In rare cases, dogs may experience mild digestive upset such as loose stool or decreased appetite. This usually resolves by lowering the dose or giving it with food.
If your dog is on medications or has complex medical conditions, it is always wise to review supplements with a professional familiar with your dog’s history.
Frequently Asked Questions
What does B6-Niacinamide help with in dogs?
It supports the nervous system, energy production, digestion, skin health, and circulation.
Is niacinamide the same as niacin?
Niacinamide is a gentler form of vitamin B3. It provides benefits without the flushing reaction associated with niacin.
How often should my dog take B6-Niacinamide?
Most dogs do well with once or twice daily dosing depending on size and needs.
Can this be used with other supplements or medications?
In most cases, yes. It is commonly used alongside other supplements. If your dog is on prescription medications, confirm compatibility first.
Is this safe for long-term use?
Yes, when used at appropriate doses. B vitamins are water soluble, which reduces the risk of accumulation.
