If you are looking for a clean, thoughtfully formulated way to support bone strength, calcium balance, immune health, and cardiovascular wellness, Vitamin D3+K2 Premier is one of the most well-designed options I have seen.
Vitamin D3+K2 by PRL: Bone, Calcium, Heart and Immune Support
The following information is a summary and review based on Dr. Candy's professional experience and recommendations. Any summary or statement has not been provided nor influenced by the manufacturer.
When I talk with clients about foundational nutrients, vitamin D almost always comes up. And for good reason. Vitamin D does far more than support bones. It plays a role in immune balance, cardiovascular health, and how the body uses calcium.
That is why I often recommend Vitamin D3+K2 Premier from Premier Research Labs. This formula pairs two essential vitamins that work best together, not alone. It is clean, plant based, and thoughtfully dosed for real clinical support.
Let me walk you through why this combination matters and how it supports whole body health.

What Is Vitamin D3+K2 Premier?
Vitamin D3+K2 Premier is a two-in-one supplement that supports how the body absorbs, uses, and directs calcium.
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Vitamin D3 helps your body absorb calcium and phosphorus from food
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Vitamin K2 helps guide that calcium into bones and teeth, not into arteries or soft tissue
This formula uses clinically relevant doses in a single capsule and delivers both vitamins in highly bioavailable, plant-based forms.
Why Vitamin D3 and K2 Belong Together
Vitamin D3 increases calcium absorption. That is essential, but it is only part of the picture.
Vitamin K2 activates proteins that tell calcium where to go. Without enough K2, calcium can end up in places you do not want it, like blood vessels.
When combined, these two vitamins support:
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Strong bones and proper mineralization
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Healthy calcium metabolism
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Cardiovascular and vascular health
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Balanced immune function
This is why pairing D3 with K2 matters so much, especially at higher D3 intake levels.
Key Health Benefits
Bone Strength and Formation
Vitamin D3 supports calcium and phosphorus absorption. Vitamin K2 supports bone formation and mineral density. Together, they help maintain strong, resilient bones over time.
Cardiovascular and Vascular Health
Vitamin K2 supports healthy arterial blood flow and vascular elasticity by helping keep calcium out of arteries. This is especially important as we age.
Immune System Support
Vitamin D3 plays a role in immune regulation and resilience, especially during seasonal challenges or periods of low sun exposure.
Calcium Balance and Utilization
This formula supports proper calcium metabolism so the mineral is absorbed efficiently and used appropriately throughout the body.

Clinically Relevant, Clean Formula
Each capsule provides:
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Vitamin D3 (as Vitashine®), 125 mcg (5,000 IU)
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Vitamin K2 (as menaquinone MK-7), 180 mcg
These are clinically established dosages, not trace amounts.
The formula also includes:
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Organic extra virgin olive oil to enhance absorption
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Plant-source vitamin E as a natural preservative
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Plant-source capsule made from cellulose and water
This supplement is:
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Plant based and vegan friendly
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Gluten free
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Non-GMO
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Screened for heavy metals and contaminants
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Manufactured in a GMP-compliant, USFDA-registered facility
Where These Vitamins Come From
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Vitamin D3 is sourced from Vitashine®, a plant-based, lichen-derived form suitable for vegetarians and vegans
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Vitamin K2 is derived from fermented natto and provided as MK-7, the most researched and bioavailable form
These sources were selected for absorption, transport, and stability in the body.

Who May Benefit Most
I often see this formula used by people who:
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Get limited sun exposure
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Are concerned about bone density
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Want cardiovascular support alongside calcium intake
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Prefer clean, plant-based supplements
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Are increasing vitamin D intake and want proper calcium balance
As always, individual needs vary, and guidance matters.
Dosage and How to Take It
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Take 1 capsule daily
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Take with a meal that contains fat for best absorption
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Follow the guidance of your healthcare professional if personalized dosing is recommended
Do not exceed recommended intake unless directed by a qualified provider.

Safety and Precautions
This supplement is well tolerated by most people.
Possible mild side effects may include digestive upset when first starting. These typically resolve quickly.
Talk with your healthcare provider before use if you:
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Have kidney disease or calcium metabolism disorders
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Are taking blood-thinning medications
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Are pregnant or nursing
Store in a cool, dry place away from heat and light.
Final Thoughts
Frequently Asked Questions
What does vitamin K2 actually do?
Vitamin K2 helps direct calcium into bones and teeth and away from arteries and soft tissues.
Why is the dose of vitamin D3 higher than typical multivitamins?
Many people are deficient in vitamin D. This formula uses a clinically relevant dose intended for meaningful support.
Is this safe to take daily?
For most people, yes, when taken as directed. Always check with your healthcare provider if you have specific medical conditions.
Can this be taken with calcium supplements?
Yes. Vitamin D3 and K2 help support proper calcium absorption and placement.
Is this product vegan?
Yes. Both vitamin D3 and K2 are plant sourced, and the capsule is vegetable based.
