If you are looking for a clean, well researched way to support energy and brain health at the cellular level, NADH Premier is one of my go to options. It works with your biology, not against it, and that is always my goal when recommending supplements.
NADH by PRL: Energy, Brain Support, Benefits, and Safe Use
The following information is a summary and review based on Dr. Candy's professional experience and recommendations. Any summary or statement has not been provided nor influenced by the manufacturer.
When someone tells me they feel tired, foggy, or just not as sharp as they used to be, I often start by looking at cellular energy. That is where NADH Premier by Premier Research Labs really shines.
This supplement is designed to support how your cells make energy, especially in the brain and muscles. When your cells have what they need, everything else tends to work better.
Let me walk you through what NADH Premier does, how it works, and who may benefit most.

What Is NADH Premier?
NADH Premier is a dietary supplement made by Premier Research Labs. It contains 10 mg of NADH per capsule.
NADH stands for nicotinamide adenine dinucleotide plus hydrogen. It is a naturally occurring coenzyme found in every living cell. A coenzyme is a helper molecule that allows important chemical reactions to happen in the body.
NADH plays a key role in cellular respiration. That is the process your cells use to turn food into usable energy called ATP. ATP is what fuels your brain, muscles, heart, and immune system.
As we age, or during periods of stress, illness, or heavy mental or physical demand, NADH levels can decline. Supplementing can help support those energy pathways.
How NADH Supports Energy and Brain Function
NADH works deep at the cellular level. Instead of stimulating the body like caffeine, it supports how energy is actually made.
Here is what that looks like in everyday terms.
- It helps your cells produce ATP, which supports steady energy
- It supports brain cells that need high energy to function well
- It helps support neurotransmitters involved in focus and alertness
- It supports oxygen utilization, which matters for endurance and stamina
Because of this, people often describe NADH as helping them feel more alert, mentally clear, and energized without feeling wired.
Key Benefits of NADH Premier
Supports Energy Production
NADH is essential for ATP production inside the mitochondria. Mitochondria are the energy factories of the cell. When this process runs smoothly, fatigue is less likely.
Supports Brain Function and Memory
The brain has very high energy demands. NADH supports cellular respiration in brain tissue, which helps support memory, focus, and mental clarity.
Supports Alertness Without Stimulation
NADH supports energy at the cellular level rather than acting as a stimulant. Many people find it helps them feel awake and focused without jitters.
Supports Oxygen Utilization
Research shows NADH can help the body use oxygen more efficiently. This is especially helpful for physical performance, endurance, and recovery.
Provides Antioxidant Support
NADH has strong free radical quenching capabilities. This means it helps neutralize oxidative stress, which supports long term cellular health.

Ingredient Breakdown and Why Each One Matters
NADH Premier keeps the formula simple and clean.
NADH (10 mg):
The active ingredient. Supports cellular energy production, brain function, oxygen utilization, and antioxidant activity.
Organic Rice Concentrate:
Used as a natural excipient. It helps maintain capsule consistency and meets Premier Research Labs quality standards.
Calcified Red Algae:
A natural source of trace minerals such as calcium and magnesium. These minerals support overall cellular and metabolic health.
Plant Sourced Capsule (cellulose, water):
A clean, plant based capsule suitable for vegetarians and vegans.
There are no synthetic fillers, no GMOs, and no unnecessary additives.

How NADH Premier Supports Whole Body Health
Because energy production touches every system, NADH Premier supports multiple areas at once.
- Brain and nervous system support
- Physical energy and stamina
- Heart muscle energy needs
- Immune cell energy demands
- Cellular repair and resilience
This is why NADH is often used in protocols focused on mental performance, fatigue, aging support, and athletic performance.
Recommended Dosage and How to Take It
According to the manufacturer:
Take 1 capsule, 2 times daily, or as directed by a health professional.
For best absorption, take NADH Premier away from food with water. Some people prefer taking it earlier in the day because of its energizing effects.
If you are sensitive or new to NADH, starting with one capsule daily and increasing as tolerated is reasonable.

Safety and Possible Side Effects
NADH Premier is generally well tolerated. Some people may experience mild effects, especially if starting at a higher dose.
Possible side effects may include stomach upset, nausea, difficulty sleeping, or feeling overstimulated.
These effects are usually temporary and dose related. If symptoms persist, stop the supplement and consult your healthcare provider.
If you are pregnant, nursing, or taking medications that affect neurotransmitters, always check with your provider before starting NADH.
Quality Standards You Can Trust
Premier Research Labs manufactures NADH Premier in the USA in a GMP compliant facility registered with the USFDA.
All ingredients are genetically tested for identity and screened for heavy metals and common contaminants. Only non GMO ingredients are used.
This level of quality matters when you are working with cellular level supplements.
Frequently Asked Questions
What does NADH Premier help with?
NADH Premier supports energy production, brain function, memory, alertness, oxygen utilization, and antioxidant protection.
Is NADH a stimulant?
No. NADH supports how cells make energy rather than stimulating the nervous system like caffeine.
How long does it take to notice effects?
Some people notice improved clarity or energy within days, while others notice more gradual benefits over several weeks.
Can athletes use NADH Premier?
Yes. NADH supports oxygen utilization and ATP production, which can benefit endurance and performance.
Is NADH Premier vegan friendly?
Yes. The capsules are plant based and suitable for vegetarians and vegans.
