Reishi Immune by PRL: Immune Balance, Stress Support, Liver Health
Reishi Immune is one of those supplements I reach for often when I want gentle, whole body immune support without overstimulating the system. It is rooted in traditional herbal wisdom and backed by modern quality standards. I appreciate how thoughtfully this formula is put together, especially for people who want immune support that also supports digestion, liver health, and stress balance.
Reishi mushrooms have been used for centuries in traditional wellness systems and were once reserved for royalty. They earned the nickname “mushroom of immortality” because of their reputation for supporting resilience and longevity. While no supplement is magic, reishi remains one of my favorite tools for supporting the body’s natural defenses in a balanced way.

What Is Reishi Immune by Premier Research Labs
Reishi Immune is a dietary supplement built around reishi mushroom, paired with supportive botanicals and minerals. It is designed to promote immune system health while also supporting liver function, digestion, and overall vitality.
This formula uses both whole reishi fruiting body and reishi fruiting body extract. That matters because different compounds are present in each form. Together, they provide broader support than either one alone.
The product is manufactured in a GMP compliant facility, screened for heavy metals and contaminants, genetically tested for potency, and made with non GMO ingredients. These details are important to me when I recommend or personally use a supplement.
Why Reishi Matters for Immune Health
Reishi is considered an immunomodulator. That means it helps the immune system respond appropriately rather than pushing it in one direction. Instead of overstimulating immune activity, reishi helps support balance.
Reishi contains naturally occurring compounds such as polysaccharides and triterpenes. These compounds help support immune cell communication and resilience. In simple terms, they help the immune system do its job without overreacting.
This makes reishi a good option for people who want daily immune support, seasonal immune support, or support during times of physical or emotional stress.

Key Benefits of Reishi Immune for People
Reishi Immune is more than a single mushroom supplement. The supporting ingredients expand its benefits beyond immunity alone.
Immune system support
Reishi helps support healthy immune response and overall immune resilience, especially during times of stress or seasonal challenges.
Stress and adaptogenic support
Reishi is classified as an adaptogen. Adaptogens help the body adapt to stress by supporting healthy adrenal and nervous system function. This can be helpful for people dealing with fatigue, tension, or ongoing stress.
Liver support and detox pathways
Milk thistle seed extract and artichoke leaf extract support healthy liver function and natural detoxification processes.
Digestive comfort
Fennel seed and artichoke support digestion and help reduce bloating and digestive discomfort.
Antioxidant protection
Reishi, turmeric, broccoli, and artichoke provide antioxidant compounds that help protect cells from oxidative stress.
Bone and mineral support
Aquamin F mineralized red algae provides naturally occurring calcium and trace minerals that support bone health and muscle function.
Powerful Ingredients in Reishi Immune
Reishi Immune is built around two primary blends, each serving a specific purpose.
Reishi Immune Blend (815 mg per serving)
This blend provides broad botanical and mineral support.
- Aquamin F mineralized red algae provides calcium and trace minerals essential for bone and cellular health.
- Organic hyssop supports respiratory and immune health.
- Artichoke leaf extract supports liver function and digestion.
- Organic turmeric provides antioxidant and inflammatory balance support.
- Milk thistle seed extract supports liver detox pathways.
- Broccoli provides phytonutrients that support cellular health.
- Organic fennel seed supports digestion and gastrointestinal comfort.
Reishi Pro Blend (395 mg per serving)
This blend focuses specifically on reishi mushroom.
- Reishi fruiting body provides whole mushroom compounds and the extract delivers concentrated bioactive components.
The capsules are made from plant sourced cellulose and water, making them suitable for vegetarians.

How Reishi Immune Supports Specific Health Needs
Immune resilience
Reishi helps support immune signaling and balance rather than overstimulation. This can be helpful for people who feel run down or want daily immune support.
Stress response and energy balance
As an adaptogen, reishi supports the body’s ability to handle physical and emotional stress. Many people notice improved resilience rather than stimulation.
Cardiovascular support
Reishi has traditionally been used to support healthy circulation and cardiovascular balance. Some compounds may support healthy cholesterol and blood pressure already within normal range.
Liver and detox support
Milk thistle and artichoke support liver enzymes and bile flow, which are important for detoxification and digestion.
Recommended Dosage and How to Take It
The manufacturer recommends taking three capsules daily or as directed by your healthcare practitioner.
I typically suggest spreading the dose throughout the day unless otherwise directed. Capsules can be taken with water. Some people prefer taking them with meals, while others do well on an empty stomach. Consistency matters more than timing.
If swallowing capsules is difficult, the capsule may be opened and mixed into food or a beverage.

Safety, Side Effects, and Precautions
Reishi Immune is generally well tolerated. Some people may experience mild effects such as digestive upset, dry mouth, dizziness, or skin itching, especially when first starting.
- Use caution if you are pregnant or breastfeeding due to limited research in these populations.
- Use caution if you take blood pressure medication, as reishi may support lower blood pressure.
- Stop use at least two weeks before surgery due to possible effects on blood clotting.
Avoid use if you have a known mushroom allergy.
As with any supplement, I recommend discussing use with your healthcare provider, especially if you take medications or manage chronic health conditions.
This product is not intended to diagnose, treat, cure, or prevent disease.
Frequently Asked Questions
What is Reishi Immune used for?
Reishi Immune is used to support immune system health, stress resilience, liver function, digestion, and overall wellness.
How often should I take Reishi Immune?
The recommended usage is three capsules daily or as directed by your healthcare practitioner.
Is Reishi Immune safe for long term use?
For most people, Reishi Immune is well tolerated when used as directed. Long term use should be discussed with a healthcare provider, especially if you take medications.
Can I take Reishi Immune if I am pregnant or breastfeeding?
If you are pregnant or breastfeeding, consult your healthcare provider before using Reishi Immune.
Is Reishi Immune non GMO and tested for purity?
Yes. Reishi Immune is made with non GMO ingredients, genetically tested for potency, and screened for heavy metals and common contaminants.
