XenoStat by PRL: Thyroid Support, Hormone Balance & Detox Care
If you are trying to support your thyroid or feel more balanced hormonally, XenoStat is a supplement I often get questions about. I want to walk you through what it is, how it works, and who it may be helpful for, in simple and practical terms.
XenoStat is made by Premier Research Labs, a company known for strict quality standards and whole-food based formulas. This product focuses on three main areas: thyroid support, hormone balance, and gentle detoxification.

What XenoStat Is and Why It Was Created
XenoStat is a botanical and marine-based supplement designed to support the body’s response to hormone-disrupting compounds. These compounds are often called xenoestrogens, which are environmental chemicals that can interfere with normal hormone signaling.
Rather than forcing hormonal changes, XenoStat supports the systems that help regulate hormones naturally, including:
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The thyroid
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The liver
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Detox pathways
A defining feature of this formula is its naturally occurring iodine from sea vegetables. Iodine is essential for thyroid hormone production, which influences metabolism, energy levels, temperature regulation, and hormone communication throughout the body.
How XenoStat Supports Thyroid and Hormonal Balance
The thyroid acts like a control center for metabolism and many hormone-driven processes. When iodine intake is too low, thyroid hormone production can suffer.
XenoStat provides iodine from whole-food marine sources rather than synthetic iodine. This matters because food-based iodine tends to be better tolerated and more gently regulated by the body.
In addition to iodine support, XenoStat helps reduce the overall toxin load that can interfere with hormone signaling. Supporting detoxification can indirectly support hormone balance, especially in people who feel sluggish, inflamed, or out of sync.
Key Ways XenoStat Supports Whole-Body Health
Thyroid support comes from naturally occurring iodine sourced from kelp and other marine plants.
Hormonal balance is supported by helping the body process and clear hormone-disrupting compounds rather than forcing hormonal changes.
Detoxification support comes from chlorella and milk thistle, which help the liver bind and remove unwanted substances.
Immune and inflammatory balance is supported by turmeric and reishi, both known for antioxidant and immune-modulating activity.
Bone and mineral support comes from Aquamin® F mineralized red algae, which provides calcium, magnesium, and trace minerals in a food-based form.
Digestive support is offered through alfalfa and hyssop, traditionally used to support gut comfort and nutrient absorption.

Ingredient Breakdown and What Each One Does
XenoStat contains two proprietary botanical blends plus naturally occurring iodine.
Botanica Detox™ (580 mg) supports detoxification and liver health. Ingredients include:
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Kelp (Ascophyllum nodosum) to supply iodine and trace minerals
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Organic chlorella with a broken cell wall to help bind unwanted compounds
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Organic milk thistle seed to support liver function
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Organic alfalfa to provide fiber, vitamins, and minerals
Botanica Support™ (296 mg) supports immune balance, inflammation control, and mineral intake. Ingredients include:
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Organic turmeric (Curcuma longa) to support a healthy inflammatory response
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Reishi mushroom (Ganoderma lucidum) to support immune modulation
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Aquamin® F mineralized red algae to supply calcium, magnesium, and trace minerals
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Organic hyssop to support digestion and respiratory comfort
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Milk thistle seed extract for additional liver support
Iodine (300 mcg) is naturally derived from marine ingredients and supports thyroid hormone production. This iodine is assayed from batch to batch and is not synthetically added.

Who May Benefit From XenoStat
XenoStat may be helpful for adults who:
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Want gentle thyroid support without synthetic iodine
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Are concerned about environmental toxin exposure
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Want to support hormone balance through nutrition and detox support
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Are looking for food-based mineral and immune support
This product is not intended to diagnose, treat, or cure disease. It is designed to support normal physiology as part of a broader wellness plan.
Dosage and How to Take XenoStat
Manufacturer recommended usage:
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Take 2 capsules daily or as directed by a health professional
Helpful tips:
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Take with meals to support absorption
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Take with a full glass of water
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Speak with your practitioner if you are using thyroid medication or have a diagnosed thyroid condition

Safety Considerations
Most people tolerate XenoStat well. Some individuals may notice mild digestive changes when starting, especially with detox-support ingredients.
Use caution if you are:
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Pregnant or nursing
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Managing a diagnosed thyroid condition
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Sensitive to iodine or marine-based ingredients
Always consult a healthcare professional before starting a new supplement.
Quality Standards and Manufacturing
XenoStat is manufactured with strict quality controls:
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Produced in the USA
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Manufactured in a GMP-compliant, USFDA-registered facility
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All ingredients genetically tested for potency and purity
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Screened for heavy metals and common contaminants
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Made exclusively with non-GMO ingredients
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Contains no synthetic fillers
Frequently Asked Questions
What is XenoStat used for?
XenoStat is used to support thyroid health, hormone balance, and detoxification using whole-food and botanical ingredients.
Does XenoStat contain synthetic iodine?
No. The iodine in XenoStat is naturally occurring from marine plant sources and is tested from batch to batch.
Can XenoStat help with hormone balance?
It supports hormone balance indirectly by supporting detox pathways, liver function, and thyroid health.
How long does it take to notice effects?
Some people notice changes in energy or digestion within a few weeks. Hormonal support is typically gradual and depends on overall lifestyle factors.
Can I take XenoStat with other supplements?
In many cases yes, but if you are using thyroid medication or other hormone-support products, it is best to check with your healthcare provider.
